AML Leukemia: Diagnosis and Treatment of Acute Myeloid Leukemia

What Is AML

  • AML is also called acute myeloid leukemia. It is a type of cancer which originates in the bone marrow and, it is quick in its development. In AML there is fast growth of abnormal white blood cells in the bone marrow.
  • It suppresses the growth of normal blood cells.
  • AML is the common type of leukemia affecting adults. Men are affected more than women. AML usually occurs at mean age of 65 yrs or in elderly individuals.
  • As the blood cells are destroyed in the bone marrow due to abnormal cells, the body eventually stops to fight infection.
  • The risk of infection increases with increased bleeding tendency.

Causes of AML Leukemia

  • The exact cause is not known, no single cause can be pinpointed. However some of the factors can lead to leukemia.
  • Environmental factors include benzene, aromatic hydrocarbons and radiation.
  • Genetic role is a factor for the disease.
  • A person has increased risk if he suffers from weakened immune system as in case of kidney transplant, Polycythemia vera a blood disorder.

Signs and Symptoms of AML Leukemia

  • Fatigue, malaise, breathlessness.
  • Fever, weight loss, bleeding gums, bruising, abnormal menses and blood in stools.
  • Pains in bone and abdominal pain.
  • Anemia and pallor.
  • Ecchymosis, purpura, fever, infection, lymph gland enlargement.


  • Complete blood count including peripheral blood smear examination.
  • Blood chemistry such as liver function test, kidney function test, calcium, phosphorus, uric acid.
  • X-ray chest
  • Bone marrow aspiration for blood examination.

Treatment of AML

  • Chemotherapy
  • Antibiotic to fight infection
  • Bone marrow transplant
  • Transfusion of red blood cell to increase hemoglobin.
  • Platelet transfusion to stop bleeding.
  • Along with conventional treatment, home remedy such as Asparagus Racemosus prevents myelosuppression caused due to chemotherapy drugs.
  • Prognosis of AML: less than one third of the patients with AML who are treated with the current intensive chemotherapy are permanently cured.
  • Younger patient response is better than elder individual. The 5 year survival rate is low in elderly individual than younger persons.
  • If the cancer does not relapse in 5 years, the person is said to be permanently cured. In most cases the cancer comes back within 2 years of diagnosis.
  • Also see how to Treat Acquired Hemoltic Anemia

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