Based on studies, there are genetic causes of psoriasis. In fact, researchers have discovered that there are nine gene mutations that could be directly involved in the formation of this skin disorder, and one of these is the one called PSORS-1.
This gene mutation is said to be the primary factor leading to psoriasis.
This is because these mutations are responsible for the abnormal functioning of certain blood cells. With psoriasis, it is the T-helper cells among the white blood cells that are largely affected.
The T-helper cells, which are considered special white blood cells, are known to function abnormally because of the mutations that cause psoriasis. These cells’ abnormal function works by attacking the skin, which in turn leads to the multiplication of skin cells at a fast rate.
This speedy skin cell multiplication results in the stacking up of skin right on the surface. Normally, the maturation of the skin formation takes 30 days. With psoriasis, however, it will only take three to six days.
Although T-cells are known for producing chemicals that aid in skin healing, this is not the case with psoriasis. Because of the abnormal production of these chemicals, inflammation happens on the joints and skin instead.
Sun exposure, smoking, and alcohol intake could also affect the frequency of psoriasis attacks and the length of flare-ups. Injuries made to the skin have also been known to lead to psoriasis.