Increase of Progesterone During Pregnancy and Its Side Effects

Progesterone and Pregnancy

Below are some facts about the important relationship of pregnancy and progesterone.

  • Progesterone is initially made by the corpus luteum in the ovary and this process is vitally needed during the first two months of pregnancy to ensure a healthy environment for the embryo. After proper implantation and towards birth, the placenta takes over the making of progesterone.

  • There is a significant increase of progesterone levels during pregnancy.

  • The production of progesterone is needed to safely maintain a healthy pregnancy and every pregnancy will result into miscarriages when the production is very low.

  • Progesterone also prepares the endometrium for the fertilized egg’s implantation by making it thick.

  • Progesterone also creates an environment full of nutrients for the growing baby by increasing glycogen and the blood in the arteries that is in the uterine lining.

  • It also prevents the uterus from having unnecessary contractions that can cause problems.

  • It significantly helps in the development of the mucous plug which keeps bacteria from reaching the uterus.

Progesterone and Pregnancy Symptoms

Progesterone is often the cause of many pregnancy symptoms. Below are some of the symptoms that are brought about by progesterone during pregnancy.

  • Progesterone along with relaxin triggers gastrointestinal discomforts during pregnancy. This is why many pregnant patients experience constipation, heartburn, indigestion, and diarrhea. It also makes the muscles in the lower intestines soft and lax which make gasses to widen the bowel making pregnant patients experience a bloating feeling.

  • Progesterone along with relaxin aids in softening cartilages and loosen joints and ligaments. These actions usually results in body aches during the last trimester of pregnancy like aches in the pubic bone and the hips.

  • Progesterone is also behind the swelling and bleeding of the gums during pregnancy. It also contributes in the development of gingivitis during pregnancy.

  • Heavy sweating even with the least movements during pregnancy is also contributed by progesterone which triggers the sweat glands to increase its secretions along with acne breakouts.

Progesterone and Pregnancy Side Effects

Progesterone has some side effects when taken as supplements by patients that have low levels of this hormone. Below are some of these side effects that can be experienced.

  • Common and transient side effects include tenderness of the breast, headache, vaginal discharge, diarrhea and problems with urination.

  • Drowsiness and dizziness.

  • Serious side effects include blood clots that can lead to heart attacks and stroke.

  • Vaginal, lumps in the breasts, uncontrollable shaking, and migraines. These side effects often need immediate medical attention.

  • Nausea, depression, edema, fatigue, preterm labor and high risks in developing cancer.

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